Skip To Main Content
Yibin Cheng on Muck Rack

Yibin Cheng

As seen in: Nature, MDPI
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Yibin

Contact Yibin, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

MTCH2 acts as a novel inhibitory receptor to suppress germ cell mitophagy by tethering BECN1, thereby maintaining mitochondrial homeostasis and male fertility

|
By Mengxing Cai, Ruifang Ren, Huiling Shu, Yanyan Yang, Longhai Dai, Yanming Dong, Yibin Cheng, Xiazhou Fu
| Nature Verified
Abstract Mitochondria play a pivotal role in spermatogenesis and male fertility, in which the selective autophagic degradation of mitochondria (mitophagy) constitutes a key process. In this study, we identify mitochondrial carrier homolog 2 (MTCH2) as a novel and critical regulator of germ cell mitophagy. Localized to the mitochondrial outer membrane (OMM), MTCH2 directly interacts with the core autophagy protein BECN1, thereby inhibiting autophagic flux and specifically suppressing mitophagy.
Open in Who Shared Issue with article?
See all 1 licensed articles (4 Total)