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Articles by Yichen Dai
Programmable Paracrine-Mimetic Microneedle System for Temporal Regulation of Cardiac Repair
1 Introduction Restoring the intricate signaling dynamics that govern tissue repair remains one of the grand challenges of regenerative medicine. For instance, following myocardial infarction (MI), the heart undergoes a tightly orchestrated sequence of inflammatory resolution, reparative remodeling, and neovascularization [1-6].
Single-cell profiling of the amphioxus digestive tract reveals conservation of endocrine cells in chordates
MATERIALS AND METHODS Amphioxus (B. floridae) obtained from a stock maintained by J.-K. Yu originating from Tampa, Florida, and all juvenile or adult animals regardless of genotype were housed in a temperature-controlled (19°C) facility at Xiamen University (115).
Evolutionary origin of the chordate nervous system revealed by amphioxus developmental trajectories - Nature Ecology & Evolution
Abstract The common ancestor of all vertebrates had a highly sophisticated nervous system, but questions remain about the evolution of vertebrate neural cell types. The amphioxus, a chordate that diverged before the origin of vertebrates, can inform vertebrate evolution. Here we develop and analyse a single-cell RNA-sequencing dataset from seven amphioxus embryo stages to understand chordate cell type evolution and to study vertebrate neural cell type origins.
Fluid Flow-Induced Modulation of Viability and Osteodifferentiation of Periodontal Ligament Stem Cell Spheroids-on-Chip
Fluid Flow-Induced Modulation of Viability and Osteodifferentiation of Periodontal Ligament Stem Cell Spheroids-on-Chip Developing physiologically relevant in vitro models for studying periodontitis is crucial for understanding its pathogenesis and developing effective therapeutic strategies.
Comparative susceptibility of SARS-CoV-2, SARS-CoV, and MERS-CoV across mammals - The ISME Journal
Abstract Exploring wild reservoirs of pathogenic viruses is critical for their long-term control and for predicting future pandemic scenarios. Here, a comparative in vitro infection analysis was first performed on 83 cell cultures derived from 55 mammalian species using pseudotyped viruses bearing S proteins from SARS-CoV-2, SARS-CoV, and MERS-CoV.
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