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Yijie Kang on Muck Rack

Yijie Kang

As seen in: BioRxiv
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Articles

Designing DNA With Tunable Regulatory Activity Using Score-Entropy Discrete Diffusion

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By Anirban Sarkar, Yijie Kang, Nirali Somia, Pablo Mantilla
| BioRxiv
Abstract Designing regulatory DNA sequences with precise, cell-type-specific activity is critical for applications in medicine and biotechnology, but remains challenging due to the vast combinatorial space and complex regulatory grammar governing gene expression.
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In Search of Transcriptomic Correlates of Neuronal Firing-Rate Adaptation across Subtypes, Regions and Species: A Patch-seq Analysis

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By John Hongyu Meng, Alan Li, Michael Feyerabend, Yijie Kang
| BioRxiv
Abstract Can the transcriptomic profile of a neuron predict its physiological properties? Using a Patch-seq dataset of the primary visual cortex, we addressed this question by focusing on spike rate adaptation (SRA), a well-known phenomenon that depends on small conductance calcium (Ca)-dependent potassium (SK) channels.
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