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Yin Dou

As seen in: Wiley Online Library, Taylor & Francis Online
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Articles

Decoding Undesirable Inflammatory Responses of Nucleic Acid-Delivering Lipid Nanoparticles

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By Ruimin Hu, Yin Dou, Chenwen Li
| Wiley Online Library Verified
1 Introduction Lipid nanoparticles (LNPs), typically formulated with ionizable lipids, helper lipids, cholesterol, and PEGylated lipids, have revolutionized nucleic acid delivery, as evidenced by the remarkable clinical success of COVID-19 mRNA vaccines [1, 2]. The ionizable lipid-mediated endosomal escape mechanism enables efficient cytosolic delivery of different nucleic acid payloads [3, 4].
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Intergovernmental network in the Yangtze River Delta megapolitan cluster: a multidimensional proximities analysis

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By Yishuai Zhang, Xin Pan, Yin Dou, Shangwu Zhang
| Taylor & Francis Online
ABSTRACT As one of the largest metropolitan clusters in China, the Yangtze River Delta (YRD) has reached the networking stage of development. The current research primarily identifies bottom-up patterns of development using big data on economic and social activities. Interaction between local governments also plays a crucial role in regional governance but lacks quantitative analysis.
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