Yin Guan
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Dual intervention on the gut and skin microbiota attenuates facial cutaneous aging
Dual intervention on the gut and skin microbiota attenuates facial cutaneous aging† The gut and skin microbiota are microbial barriers, resisting harmful foreign microorganisms and maintaining internal homeostasis. Dysbiosis of the gut and skin microbiota is involved in aging progression. However, interventions targeting facial skin wellness taking into account the gut–skin axis are scarce.
Selective and robust UPLC-MS/MS method for simultaneous quantitative determination of anlotinib, ceritinib and ibrutinib in rat plasma and its application to pharmacokinetic study
Selective and robust UPLC-MS/MS method for simultaneous quantitative determination of anlotinib, ceritinib and ibrutinib in rat plasma and its application to pharmacokinetic study Ping Du, Yin Guan, Zhuoling An, Pengfei Li and Lihong Liu Abstract A selective and robust ultrahigh performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method has been firstly developed for the simultaneous determination of three next-generation anti-tumor tyrosine kinase inhibitors (anlotinib,...
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