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Hematological Indices as Biomarkers in Patients With Rheumatoid Arthritis but Normal ESR/CRP Receiving Biological/Targeted Synthetic DMARDs
1 Introduction Rheumatoid Arthritis (RA) is an autoimmune disease causing chronic inflammatory arthritis. Biomarkers such as the erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and the 28-joint disease activity score (DAS28) are commonly utilized to assess disease severity and therapeutic response, with DAS28 serving as the primary endpoint in trials.
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