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Comparative effects of pea protein vs. dairy proteins (α-lactalbumin and casein) on aminoacidemia, exercise performance, gut microbiota, hormonal responses, neurocognitive function, mood, and metabolic–inflammatory responses in older adults
Abstract This narrative review comprehensively contrasts the physiological impacts of plant-based protein (focusing on pea protein isolates and matrices) vs. dairy-derived proteins (including intact casein and whey protein variants, emphasizing the rapid-digesting α-lactalbumin fraction).
Prognostic value and cardioprotective mechanisms of 5-methoxytryptophan in patients with acute myocardial infarction
Abstract 5-Methoxytryptophan (5-MTP) is an endogenous tryptophan metabolite with anti-inflammatory and anti-fibrotic properties. Its clinical significance in acute myocardial infarction (AMI) and underlying mechanisms remain largely unknown. In a prospective cohort, 407 AMI patients undergoing successful percutaneous coronary intervention (PCI) were enrolled. Plasma 5-MTP was measured by ELISA. SYNTAX score was used to assess coronary artery disease complexity.
Kinase Inhibitor Cardiotoxicity Database (KICDB): a causality-oriented multi-omics database for kinase inhibitor-induced cardiotoxicity
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest. DATA AVAILABILITY STATEMENT The complete, interactive database is freely and publicly accessible at https://zhanglaboratory.github.io/database/. The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions.
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