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Yin Pan on Muck Rack

Yin Pan

As seen in: Color Research & Application, Wiley Online Library, Frontiers in Immunology, MDPI, Future Medicine, Indian Journal of Pharmaceutical Sciences, Clinical Breast Cancer
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Articles

CDK4/6 inhibitors as conditional immune-priming agents in breast cancer: therapeutic windows, sequencing strategies, and rational combinations with immunotherapy, radiotherapy, and antibody-drug conjugates

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By Yin Pan
| Frontiers in Immunology
SYSTEMATIC REVIEW article Volume 17 - 2026 | doi: 10.3389/fimmu.2026.1934879 Reviewed by SYSTEMATIC REVIEW article Article metrics View details Abstract Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors are established components of endocrine therapy for hormone receptor-positive (HR+), HER2-negative breast cancer. Beyond RB-dependent G1 arrest, these drugs alter antigen presentation, interferon signaling, checkpoint-ligand expression, suppressive immune-cell populations, and CD8+ T-cell fate.
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CTSG suppresses breast cancer progression by inhibiting the EGFR/ERK signaling pathway and enhancing CD8⁺ T cell activation

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By Yin Pan
| Clinical Breast Cancer Verified
Keywords Breast cancer Cathepsin G (CTSG) EGFR/ERK CD8+ T cell activity malignant progression Get full text access Log in, subscribe or purchase for full access. References 1. Ayse Gülbin, K. ∙ Ihsan, K. ∙ Ahmet, S. ... Impact of Radiation Therapy on Serum Humanin and MOTS-c Levels in Patients with Lung or Breast Cancer Curr. Radiopharmaceut. 2024; 17:229-237 2. Mahboubeh, S. ∙ Claudia, C. ∙ Pegah, M. ...
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The natural variation in shoot Na+ content and salt tolerance in maize is attributed to various minor‐effect variants, including an SNP located in the promoter of ZmHAK11

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By xiaoyan Liang, Limin Wang, Yin Pan, Wenqi Jing
| Wiley Online Library Verified
Exclusion of Na+ from the above-ground tissues serves as an important salt-tolerant mechanism in most glycophyte plants, such as maize (Munns and Tester, 2008). Existing studies have corroborated that different maize varieties exhibit significant diversity in shoot Na+ content and then salt tolerance (Liang et al., 2024). However, the genetic basis underlying this diversity remains largely unknown, necessitating a comprehensive understanding to sustain breeding for salt-tolerant maize cultivars.
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