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Yin-ping Jia

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Articles

<i>Helicobacter pylori</i> VacA induces autophagic cell death in gastric epithelial cells via the endoplasmic reticulum stress pathway

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By Zhu-jun Zhang, Yin-ping Jia, Pan Zhu, Jun Xue
| Nature Verified
The adenovirus of the GFP-LC3B fusion protein (C3007) was obtained from Beyotime Institute of Biotechnology. Some chemical reagents were purchased from Sigma, including 3-MA (M9281), Baf A1 (B1793), thapsigargin (T9033), AO (A8097), MDC (30432), and carbobenzoxy-valyl-alanyl-aspartyl-[O-methyl]-fluoromethyl ketone (Z-VAD-FMK, V116); antibodies against autophagy-related protein 12 (ATG12, WH0009140m1), TRIB3 (WH0057761M3), and MAP1LC3B (L7543) were also obtained from Sigma.
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TLR2/TLR4 activation induces Tregs and suppresses intestinal inflammation caused by Fusobacterium nucleatum in vivo

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By Kun Wang, Yin-ping Jia, Zhu-jun Zhang, Ya-nan Tong
| PLOS
Toll-like receptors (TLRs) 2 and 4 play critical roles in intestinal inflammation caused by Fusobacterium nucleatum (F. nucleatum) infection, but the role of TLR2/TLR4 in regulation of proinflammatory cytokines remains unknown. In this study, through microarray analysis and qRT-PCR, we showed that TLR2/TLR4 are involved in the F. nucleatum-induced inflammatory signaling pathway in Caco-2 cells, C57BL/6 mice and human clinical specimens. In TLR2-/- and TLR4-/- mice, F.
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