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Yinchao Hong

As seen in: Nature
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Articles

Functional connectivity density alterations in obsessive-compulsive disorder are associated with neurotransmitter and genetic profiles

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By Ke Chen, Yueling Liu, Yian Xiao, Siya Zhu, Woxin Pan, Qiang Hua, Ke Wan, Jiarui Ye, Kai Wang, Chunyan Zhu, Fuyao Cao, Weihang Weng, Yinchao Hong, Zhisen Li, Shuoqi Xiang, Fengqiong Yu, Gongjun Ji
| Nature Verified
Abstract Obsessive-compulsive disorder (OCD) is characterized by disrupted brain network organization, yet the molecular basis underlying this dysconnectivity remains elusive. Here, we applied voxel-wise functional connectivity density (FCD) mapping to characterize brain network alterations across 145 patients with OCD and 168 healthy controls (HCs), while further evaluating its ability to support diagnostic classification and predict treatment response in OCD.
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