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A dynamic nomogram for predicting pathologic complete response to neoadjuvant chemotherapy in locally advanced rectal cancer
1 INTRODUCTION Presently, the standard of treatment for locally advanced rectal cancer (LARC) continues to recommend radical resection after neoadjuvant chemoradiotherapy (nCRT).1 It is generally recognized that pathologic complete response (pCR) is associated with better overall survival (OS) (HR = 0.50; p < 0.001) and disease-free survival (DFS) (HR = 0.49; p < 0.001) in patients with digestive cancer compared to non-pCR.2 In addition, for patients with pCR, a “watch and wait” or local...
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