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Protective Effects of Hyperoside on Type 2 Diabetes Through the Regulation of Pancreatic β-cell Function
1 Introduction Type 2 diabetes, the predominant type of diabetes mellitus, is characterized by insulin resistance and β-cell dysfunction. More than 90% of diabetes cases are type 2 resulting from defective insulin action or insulin resistance [1]. T2D usually develops due to insulin resistance in peripheral tissues rather than in pancreatic β-cells, with increasing incidence and mortality rates, affecting about 500 million people worldwide [2].
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