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Yinding Peng on Muck Rack

Yinding Peng

As seen in: Frontiers in Immunology
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Integration of single-cell and bulk RNA sequencing data identified an aortic dissection-enriched ANGPTL4+ macrophage subpopulation

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By Zhenghao Li, Haonan Chen, Xuanyu Liu, Yue Shao, Qingchen Wu, Haoming Shi, Cheng Zhang, Yinding Peng
| Frontiers in Immunology
Abstract Background: Macrophages play an indispensable role in the pathogenesis of aortic dissection (AD). However, the underlying molecular and cellular mechanisms remain incompletely understood. Methods: We integrated six publicly available single-cell RNA sequencing (scRNA-seq) datasets and constructed an atlas of AD, identifying an AD-enriched ANGPTL4+ macrophage subpopulation. Subsequent comprehensive bioinformatic analyses explored its potential mechanisms in AD.
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