Yinfeng Chen

Abstract Diabetic kidney disease (DKD) is a microvascular complication of diabetes and a major cause of kidney failure; current treatment methods still need improvement. Sirtuin 3 (SIRT3) is an NAD+-dependent protein deacetylase located in the mitochondria, where it regulates the activity and biological functions of diverse proteins and influences various mitochondrial functions via deacetylation. Increasing research indicates that SIRT3 holds promise as a therapeutic target for DKD.

1. Introduction The Internet of Things (IoT) is gradually developing as an emerging global Internet-based information architecture that facilitates the exchange of goods and services [1,2,3,4]. In a traditional IoT model, service providers typically rely on centralized servers to execute tasks. However, this service model suffers from several challenges, including centralization and security issues.

Back to Journals » Diabetes, Metabolic Syndrome and Obesity » Volume 17 Authors Chen Y, Wang X, Min J, Zheng J, Tang X, Zhu X, Yu D, Jin D Received 29 October 2023 Accepted for publication 1 February 2024 Published 13 February 2024 Volume 2024:17 Pages 739—757 DOI https://doi.org/10.2147/DMSO.S443352 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Prof.