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Yinfeng Yuan

As seen in: Nature
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A circuit linking dentate gyrus and retrosplenial granular cortex regulates fracture healing in male mice

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By Wei Zhang, Yue Guo, Danni Chen, Xiaowen Jiang, Jingjing Zhang, Erman Chen, Wanyi Wu, Yiming Qian, Xiaohua Yu, Yongjie Wang, Weixu Li, Yinfeng Yuan
| Nature Verified
Abstract Traumatic brain injury often accelerates fracture repair, but the neural circuits linking brain state to bone healing remain unclear. Here we show that, in male mice, a hippocampal–cortical circuit linking the dentate gyrus (DG) and the retrosplenial granular cortex (RSGc) regulates repair after bone injury. Skeletal injury increased activity–associated labeling in both regions.
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