Ying Bei

1 Introduction Hydrogels are 3D networks of hydrophilic polymers that can be physically or chemically crosslinked.[1] The unique tunable physical properties, intricate structure, and exceptional biocompatibility of these materials enable them to faithfully mimic tissue and cellular microenvironments, rendering them indispensable multifunctional soft materials with diverse applications in the fields of biotechnology and biomedical research, encompassing actuators, sensors, artificial muscles,...

Please use this identifier to cite or link to this item: http://dx.doi.org/10.25673/109926 Title: Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer Type: Article Language: English Abstract: Molecular routes to metastatic dissemination are critical determinants of aggressive cancers. Through in vivo CRISPR–Cas9 genome editing, we generated somatic mosaic genetically engineered models that faithfully recapitulate metastatic renal tumors.