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Ying-Chen Zhou on Muck Rack

Ying-Chen Zhou

As seen in: MDPI, Royal Society of Chemistry
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Articles

Rapid and Highly Sensitive Immunosorbent Assay to Monitor Helicases Unwinding Diverse Nucleic Acid Structures

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By Ying-Chen Zhou, Xiu-Cai Chen, Jia-En Wang, Bi-Han Wu
| Royal Society of Chemistry Verified
Rapid and Highly Sensitive Immunosorbent Assay to Monitor Helicases Unwinding Diverse Nucleic Acid Structures Jia-En Wang, Ying-Chen Zhou, Bi-Han Wu, Xiu-Cai Chen, Junqiu Zhai, Jia-Heng Tan, Zhi-Shu Huang and Shuo-Bin Chen Abstract Helicases are crucial enzymes for DNA and RNA metabolism, which function by unwinding particular nucleic acid structures. However, most convenient and high-throughput helicase assays were limited on the typical duplex DNA.
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Fluorescent Quinolinium Derivative as Novel Mitochondria Probe and Function Modulator by Targeting Mitochondrial RNA

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By Yu-Wei Lin, Xiu-Cai Chen, Bo-Zheng Wang, Ying-Chen Zhou
| MDPI
Abstract : Mitochondria have a crucial role in regulating energy metabolism and their dysfunction has been linked to tumorigenesis. Cancer diagnosis and intervention have a great interest in the development of new agents that target biomolecules within mitochondria. However, monitoring and modulating mitochondria RNA (mtRNA), an essential component in mitochondria, in cells is challenging due to limited functional research and the absence of targeting agents.
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