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Structural and dynamic insights into ligand recognition and activation of somatostatin receptor 3 - Acta Pharmacologica Sinica
Abstract Somatostatin receptor 3 (SSTR3) exerts critical biological functions such as negatively regulating hormone release and cell proliferation, making it a promising therapeutic target for endocrine disorders and nonfunctioning pituitary tumors. However, the development of more effective and safer somatostatinergic therapies is limited due to a lack of molecular understanding of the ligand recognition and conformational dynamics of SSTR3.
Metal-Free Selective Ortho-C-H Amidation of Hypervalent(III) Iodobezenes with N-Methoxy Amides under Mild Conditions
CCDC 2010310−2010311 and 2010462 contain the supplementary crystallographic data for this paper. These data can be obtained free of charge via www.ccdc.cam.ac.uk/data_request/cif, or by emailing data_request@ccdc.cam.ac.uk, or by contacting The Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, UK; fax: +44 1223 336033. Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions.
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