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Ying Hao on Muck Rack

Ying Hao

As seen in: Color Research & Application, Nature, Wiley Online Library, arXiv, Memory Studies, Frontiers, Frontiers in Public Health, MDPI, SAGE Publishing, ACS Publications and
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Articles

APOE genotypes differentially remodel the astrocytic lipid droplet proteome to shape lipid droplet dynamics

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By Carla Cuní-López, Jessica Root, Ying Hao, Niek Blomberg, Dylan C. Sacks, Amber E Trujillo, Rodolfo Ghirlando, Isabelle Kowal, Jacob Epstein, Linda Yang, Mark R. Cookson, Elise Marsan, Rik van der Kant, Martin Giera, Yue Qi, Priyanka Narayan, Sascha J. Koppes-den Hertog
| Nature Verified
Abstract Lipid droplets are dynamic cellular organelles that store neutral lipids and coordinate metabolic and stress-response pathways. In the brain, lipid droplets in glial cells, including astrocytes, have been implicated in Alzheimer’s disease, but how genetic risk factors influence their composition and turnover remains poorly understood. APOE is the strongest genetic modulator of late-onset Alzheimer’s disease and exists in common variants that confer decreased, neutral, or increased risk.
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A Proteomic Resource of Human iPSC-derived Neurons Exposed to Neurotropic Viruses

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By Ziyi Li, Negin P. Martin, Jacob Epstein, Shih-Heng Chen, Ying Hao, Daniel Ramos, Kate Andersh, Paige B Jarreau, Cory A. Weller, Marianita Santiana, Benjamin Jin, Caroline B Pantazis, Luigi Ferrucci, Mark R. Cookson, Andrew Singleton, Yue Qi, Jerrel L. Yakel
| Nature Verified
Abstract Viral infections are common across the human lifespan, yet their molecular effects on human neurons remain poorly characterized. We present a mass spectrometry (MS)-based proteomic dataset profiling human induced pluripotent stem cell (iPSC)-derived neurons following exposure to five neurotropic viruses: Herpes simplex virus 1 (HSV-1), Human coronavirus 229E (HCoV-229E), Epstein-Barr virus (EBV), Varicella-Zoster virus (VZV), and Influenza A virus (H1N1).
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Endothelial Cell Proteins as Biomarkers in Susac Syndrome

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By Rohit Ninan Benjamin, Yue Qi, Ying Hao
| Wiley Online Library Verified
BBB Blood–brain barrier CD8+ Cluster of differentiation 8–positive CSF Cerebrospinal fluid DIA-MS Data-independent acquisition mass spectrometry FLAIR Fluid-attenuated inversion recovery IL6ST Interleukin-6 signal transducer LC Liquid chromatography LRP1 Low-density lipoprotein receptor–related protein 1 MCAM Melanoma cell adhesion molecule mRS Modified Rankin Scale MS Mass spectrometry NECTIN2 Nectin cell adhesion molecule 2 SELP P-selectin SLC27A4 Solute carrier family 27 member 4 SS Susac...
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