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Ying-Hua Chuang on Muck Rack

Ying-Hua Chuang

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Sulfated PSGL-1 primes the enterovirus A71 fivefold vertex for localized remodeling

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By Ya-Na Wu, Wen-Shuo Kuo, Chun-Hsiung Wang, Ching-Kun Chang, Guan-Wen Chen, Nai-Hsiang Chung, Yu-Shan Hsieh, Ying-Chin Chen, Shu-Ling Yu, Shang-Rung Wu, Yen-Hung Chow, Ying-Hua Chuang, Tzu-Chi Chuang
| Nature Verified
Abstract Enterovirus A71 (EV-A71) causes hand, foot, and mouth disease and poses a significant public health threat through severe neurological complications in pediatric cases. P-selectin glycoprotein ligand-1 (PSGL-1) functions as an attachment factor, yet the structural basis of PSGL-1 recognition on the EV-A71 capsid has remained undefined.
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