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Articles

Semaphorin 4D Promotes Skeletal Metastasis in Breast Cancer

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By Ying-Hua Yang, Asma Buhamrah, Abraham Schneider, Yi-Ling Lin
| pubpeer.com
Comment PLoS ONE (2016) - pubmed: 26910109 doi: 10.1371/journal.pone.0150151 issn: 1932-6203 Ying-Hua Yang, Asma Buhamrah, Abraham Schneider, Yi-Ling Lin, Hua Zhou, Amr Bugshan, John R. Basile
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Semaphorin 4D Promotes Skeletal Metastasis in Breast Cancer

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By Diagnostic Sciences, Ying-Hua Yang, Asma Buhamrah, Abraham Schneider
| PLOS
Bone density is controlled by interactions between osteoclasts, which resorb bone, and osteoblasts, which deposit it. The semaphorins and their receptors, the plexins, originally shown to function in the immune system and to provide chemotactic cues for axon guidance, are now known to play a role in this process as well.
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