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Ying Huai on Muck Rack

Ying Huai

As seen in: Nature, Wiley Online Library, Royal Society of Chemistry
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Articles

Salidroside ameliorates glucocorticoid-induced osteoporosis by regulating the PI3K/Akt/mTOR pathway: a network pharmacology and in vivo

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By Kun Ren, Ying Huai, Xin Dong, Zhiwen Luo, Peng Wu, Xiajun Liang
| Nature Verified
Abstract Osteoporosis (OP) is a bone disorder, common cause of bone fracture and disability. Management of it needs development of an alternative medicine and present report evaluates the protective effect of salidroside against glucocorticoid induced osteoporosis in rat model. Network pharmacology and docking study was performed to determine the molecular targets of salidroside against osteoporosis and its interaction with these targets.
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HuR‐positive stress granules: Potential targets for age‐related osteoporosis

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By Ying Huai, Xue Wang, Wenjing Mao, Xuehao Wang
| Wiley Online Library Verified
ActD actinomycinD ADME absorption, distribution, metabolism and excretion ALPL alkaline phosphatase α-MEM alpha-minimum essential medium API apigenin ARS alizarin redS BMD bone mineral density BMSCs bone marrow-derived mesenchymal stem cells BV/TV bone volume/tissue volume CMC-Na sodium carboxymethyl cellulose Co-IP co-immunoprecipitation COL1A1 collagen type I alpha 1 CSF-1R colony-stimulating factor 1 receptor DAPI 4’,6-diamidino-2-phenylindole DMSO dimethylsulfoxide FBS fetal bovine serum...
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Bergamottin promotes osteoblast differentiation and bone formation via activating Wnt/β-catenin signaling pathway

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By Xue Wang, Chong Chia Yin, Xuechao Liang, Ying Huai
| Royal Society of Chemistry Verified
Bergamottin promotes osteoblast differentiation and bone formation via activating Wnt/β-catenin signaling pathway Osteoporosis is one of the most common bone disorders that seriously affect the health and life quality of elderly individuals. Reduced osteoblast differentiation and bone formation lead to changes in bone volume and microarchitecture, leaving the bones vulnerable to fracture.
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