Ying Jane Ou
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Bioinformatics‐Driven Design of Peptides for Membrane Stabilization During Cryopreservation
Conflict of Interests The authors declare no conflict of interest. Supporting Information Filename Description anie202516336-sup-0001-SuppMat.docx130 MB Supporting Information References 1, in Thermodynamics and Biophysics of Biomedical Nanosystems, Series in BioEngineering, 2019, 39–61. 2, , Bba-Biomembranes 2004, 1666, 142–157, https://doi.org/10.1016/j.bbamem.2004.08.002. 3, Annu Rev Plant Phys 1984, 35, 543–584, https://doi.org/10.1146/annurev.pp.35.060184.002551.
Microscopic Insights into Ring-Opening Reaction of Ethylene Carbonate on LiCoO2 by On-the-Fly Machine Learning Molecular Dynamics The cathode-electrolyte interface plays a crucial role in determining the structural stability, electrochemical behavior and cycling performance of Li-ion batteries (LIBs). However, the dynamic structural evolution and microscopic reaction mechanisms at the interface remain poorly understood.
Quantitative Systems Pharmacology Model to Predict Target Occupancy by Bruton Tyrosine Kinase Inhibitors in Patients With B‐Cell Malignancies
What is the current knowledge on the topic? ○ Despite small numerical differences in Bruton tyrosine kinase (BTK) occupancy in peripheral blood mononuclear cells (PBMCs) and lymph nodes (LNs) among the three approved BTK inhibitors, the randomized phase 3 progression-free survival data show zanubrutinib is superior to ibrutinib, whereas acalabrutinib is noninferior to ibrutinib. BTK occupancy data from deep target tissues such as bone marrow (BM) and LNs are relatively scarce.
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