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rhCC16 Suppresses Cellular Senescence and Ameliorates COPD‐Like Symptoms by Activating the AMPK/Sirt1‐PGC‐1‐α‐TFAM Pathway to Promote Mitochondrial Function
1 Introduction Chronic obstructive pulmonary disease (COPD) is a common disease of the lung that causes irreversible damage to the alveolar wall and leads to inflammatory cell infiltration and fibrosis around the airways. The morbidity and fatality rates associated with COPD increase with age [1]. Recent studies conducted in China have revealed several independent risk factors for COPD, including age, history of smoking, sex, and education level, among others [2].
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