Ying Jin
As seen in:
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arXiv,
PLOS ONE,
BMJ Open Respiratory Research,
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Frontiers,
MDPI
and
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Vitamin B5 supports anti-PD1 response in HER2-positive gastric cancer and enhances interaction between naïve B cells and T cells
Abstract The cellular mechanisms underlying HER2-positive gastric cancer (HER2+ GC) responses to immunochemotherapy remain underexplored. Here, we perform longitudinal single-cell RNA-sequencing with paired TCR/BCR profiling on HER2+ and HER2-negative gastric cancer (HER2− GC) pre- and post-treatment to find dynamic immune remodeling during. Pre-treatment HER2+ GC displays an immunogenic microenvironment enriched with tumor-reactive T and B cells compared to HER2− GC.
Chromosome-level genome assembly and annotation of the black-spot snapper, Lutjanus fulviflamma
Abstract Lutjanus fulviflamma is a commercially significant offshore warm-water fish species predominantly inhabiting shallow marine environments. Previous studies have primarily concentrated on the development of genetic markers and evolutionary relationships. In this study, a chromosome-level reference genome was constructed through the integration of three sequencing techniques: Illumina de novo, Hi-C, and PacBio.
Single-cell transcriptomic analysis reveals the immunosuppressive status of NK cell subpopulations in TNBC
Loading metrics Open Access Peer-reviewed Research Article Citation: Liu Y, Cao W-M, Jin Y, Xu W (2026) Single-cell transcriptomic analysis reveals the immunosuppressive status of NK cell subpopulations in TNBC. PLoS One 21(7): e0354524. https://doi.org/10.1371/journal.pone.0354524 Editor: UDAYAN BHATTACHARYA, Weill Cornell University, UNITED STATES OF AMERICA Received: March 2, 2026; Accepted: July 9, 2026; Published: July 23, 2026 Copyright: © 2026 Liu et al.
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