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Tobacco smoking-induced glucose metabolic reprogramming in chronic obs
Introduction Chronic obstructive pulmonary disease (COPD) is a prevalent and heterogeneous respiratory disorder characterized by irreversible airflow limitation and chronic respiratory symptoms, with primary clinical phenotypes including chronic bronchitis and emphysema.1,2 In 2022, the Lancet COPD Commission categorized COPD into five types based on the major risk factors and emphasized that distinct pathophysiological mechanisms driven by these risk factors may translate into differentiated...
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