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Ying-Ming Tsai on Muck Rack

Ying-Ming Tsai

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Single-cell and spatial transcriptomics map lung-adaptive metastasis programs through Exoc4, Cd36–vasculogenic mimicry, and Cxcr2 signaling in triple-negative breast cancer

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By Chia-Yu Kuo, Fang-Ming Chen, Ming-Feng Hou, Hung-Pei Tsai, Yu-Yuan Wu, Ling-Yu Wu, Ya-Ling Hsu, Hsiao-Chen Lee, Kai-Chien Chuang, Sheng-Feng Pan, Ying-Ming Tsai
| Nature Verified
Abstract Triple-negative breast cancer (TNBC) is an aggressive subtype associated with high metastatic potential and poor outcomes, with lung metastasis representing one of the most frequent and life-threatening events. However, the mechanism how cellular plasticity and reprogramming that enable TNBC cells to colonize in the lung remain incompletely understood.
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