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Ying-nan Liu on Muck Rack

Ying-nan Liu

As seen in: Nature, Royal Society of Chemistry, Canadian Journal of Infectious Diseases & Medical Microbiology
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Articles

PIEZO1-mediated endometrial decidualization is disrupted in miscarriage through BECN1-dependent autophagy

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By Jin-Wen Kang, Yao Wu, Yu An Zhang, Hui-Xia Li, Yao-Feng Yang, Xiao-Qing Huang, Jia-Ying Yu, CHEN LIANG, Rui Zhang, Xiao-Zheng Liu, Shan-Shan Song, Ying-nan Liu, Aftab Shaukat, Yong Song, Bin Guo, Zeng-Ming Yang, Asgerally T. Fazleabas, Ren-Wei SU, Guang-Ya Li, Samantha Hrbek, Hong-Lu Diao
| Nature Verified
Abstract Miscarriage is a major challenge in reproductive medicine, with impaired decidualization as a key contributing factor. The mechanosensitive ion channel PIEZO1 responds to mechanical forces including shear stress, stretch, and extracellular matrix (ECM) stiffness. Here, we report that PIEZO1 is decreased in decidua from miscarriage patients and show it plays a crucial role in decidualization in response to ECM stiffness and cell contraction.
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Vanillin Prevents the Growth of Endometriotic Lesions through Anti-inflammatory and Antioxidant Pathways in Mouse Model

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By Ying-nan Liu, Jin-Wen Kang, Yu Zhang, Shan-Shan Song
| Royal Society of Chemistry Verified
Vanillin Prevents the Growth of Endometriotic Lesions through Anti-inflammatory and Antioxidant Pathways in Mouse Model Ying-Nan Liu, Jin-Wen Kang, Yu Zhang, Shan-Shan Song, Qi-Xin Xu, Han Zhang, Lei Lu, Shu-Wen Wei, Chen Liang and Ren-Wei Su Abstract Endometriosis is an estrogen-dependent chronic inflammatory gynecological disease defined by the presence of endometrial glands and mesenchyme outside the uterine cavity, named ectopic endometrium.
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