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Ying-Qi Yu

As seen in: Royal Society of Chemistry
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Articles

New Insights on the Size-Dependent Inhibition of Enzymes by Gold Nanoparticles

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By Wen-Qi Chen, Wen-Jing Wu, Ying-Qi Yu, Yi Liu
| dx.doi.org
Particle size might affect the inhibition behaviors of gold nanoparticles (AuNPs) on enzyme activity by influencing the density of binding sites (ρ), the association constant (Ka), the steric hindrance of enzymes by AuNPs, the binding orientations of the enzyme on AuNPs, as well as the structural changes of enzymes.
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Design and construction of competitive, noncompetitive and uncompetitive nano inhibitors of enzymes

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By Ying-Qi Yu, Ling Cao, Miao-Miao Yin, Wen-Qi Chen
| Royal Society of Chemistry Verified
Design and construction of competitive, noncompetitive and uncompetitive nano inhibitors of enzymes† Wen-Qi Chen,a Ying-Qi Yu,a Ling Cao,a Miao-Miao Yin,b Yi Liu ac and Feng-Lei Jiang *a Abstract Three common types of reversible inhibitors, namely competitive, noncompetitive and uncompetitive inhibitors, were designed and constructed by using enzymes with different surface charges and gold nanoparticles with different surface ligands and particle sizes.
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