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Development of a predictive model for pancreatic cancer integrating serum metabolomics and polygenic risk score
Abstract Background: Pancreatic cancer (PC) is highly aggressive and associated with extremely poor prognosis. Due to the lack of specfic symptoms in the early stage, most patients have already lost the opportunity for curative surgical resection at the time of diagnosis. Therefore, improving the early identification of individuals at elevated risk of PC is clinically important. Methods: Using data from the UK Biobank, 157,235 participants were included.
The Depletion of Plasma Cells but Not CD20+B Cells Alleviates Primary Biliary Cholangitis
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description liv70373-sup-0001-TableS1-S2-FigureS1-S3.docxWord 2007 document , 1 MB Table S1: Criteria for liver histopathological evaluation in patients with PBC. Table S2: Sequences of primers used in the study. Figure S1: Hepatic infiltration of B cells correlated with disease severity in PBC patients.
In vitro validation of a novel disposable leukocyte remover to remove | JIR
Back to Journals » Journal of Inflammation Research » Volume 18 Authors Zheng Y, Ran Y, Wu J, Yang P, Liao X, Zhang J, Meng W, Gou D, Li L, Du L, Lin J Received 18 December 2024 Accepted for publication 4 April 2025 Published 18 April 2025 Volume 2025:18 Pages 5355—5370 DOI https://doi.org/10.2147/JIR.S503575 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Qing Lin Yuling Zheng,1,2 Ying Ran,3 Juan Wu,1 Ping Yang,1...
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