Ying Shen
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Metabolic control of smooth muscle cell phenotype switching in atherosclerosis
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share This article has 0 eLetter . Abstract The loss of smooth muscle cell (SMC) contractile phenotype contributes to various diseases including atherosclerosis. However, its metabolic basis is not entirely elucidated.
Association Between Cardiovascular Health and Pelvic Inflammatory Disease among US Adults: A Cross-Sectional Study From NHANES 2013-2023
The authors have declared no competing interest. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Not Applicable The details of the IRB/oversight body that provided approval or exemption for the research described are given below: This study utilized de-identified, publicly available data from the National Health and Nutrition Examination Survey (NHANES).
Computer Science > Machine Learning
Online reinforcement learning is widely used to align large language models (LLMs) with reward signals, yet training can be unstable under noisy or misspecified rewards. We identify a failure mode we call directional inconsistency: within a batch, a small set of high-reward rollouts induces representation-space preference directions that sharply disagree with the batch majority, resulting in high-variance and destabilizing updates.
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