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Ying Sheng on Muck Rack

Ying Sheng

As seen in: Nature, Wiley Online Library, arXiv, PLOS, Frontiers, MDPI, ACS Publications, Royal Society of Chemistry, BioRxiv
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Articles

Integrating zero-inflation correction and transcriptional kinetics for single-cell transcriptomic analysis

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By Chengkai Yang, Yu Sheng Liao, Ying Sheng
| PLOS
In previous analyses, synthetic datasets were generated based on the basic telegraph model and negative binomial distribution.
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E3 ligase LMO7 promotes ALKBH2 ubiquitination to sensitize MGMT-deficient glioblastoma to temozolomide

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By Zhiming Sun, Yue Liu, Liyuan Zeng, Ye Liu, Zhaohui Liu, Jiabing Li, Ying Sheng, Yu Zhao, Yunfang Deng, Chujing He, Yuqiao Cai, Yuyao Xue
| Nature Verified
Abstract Temozolomide (TMZ) resistance in glioblastoma (GBM) is often linked to high MGMT protein levels, but MGMT-deficient tumors can still acquire resistance, implicating MGMT-independent repair pathways. Here, we identify an oxidative stress-responsive LMO7–ALKBH2 ubiquitination mechanism that regulates ALKBH2 stability and modulates alkylation damage tolerance in GBM.
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DeepSeek-V4 on Day 0: From Fast Inference to Verified RL with SGLang and Miles

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By Tom Chen, Ying Sheng, Mingyi Lu
| lmsys.org
The SGLang and Miles TeamApril 25, 2026 We are thrilled to announce Day-0 support for DeepSeek-V4 across both inference and RL training. SGLang and Miles form the first open-source stack to serve and train DeepSeek-V4 on launch day — with systems purpose-built for its hybrid sparse-attention architecture, manifold-constrained hyper-connections (mHC), and FP4 expert weights. Figure 1. Decode throughput of SGLang vs the other OSS engine on a 30K-token prompt truncated from "Dream of the Red Chamber".
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