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Ying Shi

As seen in: Arthritis & Rheumatology, Color Research & Application, Nature, Wiley Online Library, Cambridge University Press & Assessment, Memory Studies, New Phytologist, PLOS, PLOS Medicine, PLOS ONE and
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Articles

Single-nucleus transcriptomics-based drug screening platform for focal cortical dysplasia

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By Chuantao Fang, Guilin Meng, Lin Yang, Lijun Wang, Yanfeng Tan, Jingjing Guo, Ying Shi, Xianming Liu, Rui Zhao, Min Zhang, Fang Yuan, Dashi Qi
| Nature Verified
Abstract Focal cortical dysplasias (FCDs) are a major cause of drug-resistant epilepsy, yet their molecular and pathological complexity has limited the development of effective antiseizure medications. Here, we performed single-nucleus RNA sequencing on 49 human neocortical specimens spanning FCDI-III.
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Effects of chronic jetlag on high-fat and high-fructose diet induced renal injury in mice

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By Lin Xing, Junyan Xie, Ying Shi, Ruoyi Zheng, Tao Zhang, Xuejing Li, Zhijun Zhou, Dongmei Zhang
| Nature Verified
Abstract Chronic disruption of the circadian rhythm caused by factors such as jetlag has been associated with increased risks of obesity and chronic kidney disease. Although obesity is a well-known contributor to renal injury, the impact of circadian misalignment on obesity-related kidney disease (ORKD) remains unclear. This study aimed to investigate whether chronic jetlag exacerbates ORKD and to explore its association with the NLRP3/Caspase-1/IL-1β inflammasome signaling pathway.
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Plasmonic–cavity hybrid relative humidity sensor based on Ag nanobowl arrays integrated with a poly(vinyl alcohol) film

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By Ying Shi, Yue Zhao, Haibin Ni
| Optica Verified
The growing demand for relative humidity (RH) monitoring in environmental assessment, industrial process control, and localized microenvironment surveillance has stimulated research on highly sensitive optical humidity sensing schemes amenable to spectral demodulation. Here, we present a plasmonic–cavity hybrid optical humidity sensor that integrates a silver (Ag) nanobowl array with a poly(vinyl alcohol) (PVA) film.
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