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Ying Tang

As seen in: Arthritis & Rheumatology, Color Research & Application, Nature, Wiley Online Library, arXiv, PLOS ONE, BFM TECH & CO, Frontiers, Frontiers in Immunology, Frontiers in Physiology and
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Articles

Macrophage pyroptosis driven by Omicron variant’s distinct entry route underlies severe disease pathogenesis

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By Han-Bing Chen, Hao Zheng, Chao Gao, Ying Chi, Ying Tang, Wei Huang, Feng Guo, Ke-Xin Li, Shu-Feng Li, Tao Liu, Hai-Bo Qiu, Jie Chao, Jian-Feng Xie
| Nature Verified
Abstract Severe disease due to SARS-CoV-2 infection is a primary driver of healthcare burden throughout the pandemic. Although the overall pathogenicity of the Omicron variant is attenuated compared with earlier strains, mortality among patients who develop severe disease following Omicron infection remains substantial, and the underlying mechanisms remain unclear.
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Gut microbiota-activated PLCγ2 monocytes drive atrial fibrillation

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By Pinfang Kang, Dimin Wang, Peng Teng, Wenjie Diao, Yi Zhao, Qing Chen, Ying Tang, Ziyi Chen, Zhengyu Sun, Wenjuan Wu, Hongju Wang, Weidong Li, Bi Tang, Liang Ma, Meiyang Xu, Jinjin Meng
| Nature Verified
Abstract Atrial fibrillation (AF) is the most common sustained arrhythmia, conferring risks of stroke and heart failure. Monocyte activation-associated inflammation is implicated in AF, yet the recruitment of monocytes and their role in atrial remodeling remain unclear. Here we show that monocytes from AF patients upregulate phospholipase C gamma 2 (PLCG2).
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Protective effects and mechanisms of puerarin in ovariectomized animal models of osteoporosis: a systematic review and meta-analysis of preclinical studies

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By Chao Dong, Zhixun Guo, An Hu, Liyang Zhao, Ying Tang, Yexin Chen, Zhichao Ruan, Yixin Ma, Xinyu Wang, Jiangteng Liu
| Frontiers in Physiology
Abstract Background: Osteoporosis is a prevalent systemic metabolic disease, and osteoporotic fractures severely compromise patients’ health and quality of life. Postmenopausal osteoporosis is a major form of primary osteoporosis in women and is primarily attributable to estrogen deficiency. Ovariectomized animal models are widely used to reproduce estrogen deficiency–induced bone loss and microarchitectural deterioration.
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