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Ying Taur

As seen in: Nature, Science Magazine, The ASCO Post
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Articles

Antifungal heteroresistance causes prophylaxis failure and facilitates breakthrough Candida parapsilosis infections - Nature Medicine

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By Bing Zhai, Chen Liao, Oliver Bader, Ying Taur, Geraldine Butler, João Xavier, David Weiss Verified
| Nature Verified
Abstract Breakthrough fungal infections in patients on antimicrobial prophylaxis during allogeneic hematopoietic cell transplantation (allo-HCT) represent a major and often unexplained cause of morbidity and mortality. Candida parapsilosis is a common cause of invasive candidiasis and has been classified as a high-priority fungal pathogen by the World Health Organization.
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Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease - Nature Microbiology

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By Sarah Lindner, Oriana Miltiadous, Anastasia I Kousa, Nicholas Waters, Kristen Victor, Sebastien Monette, Ying Taur, Miguel-Angel Perales, Jonathan Peled, Clarissa Campbell, Jenny Paredes
| Nature Verified
Abstract Microbial transformation of bile acids affects intestinal immune homoeostasis but its impact on inflammatory pathologies remains largely unknown. Using a mouse model of graft-versus-host disease (GVHD), we found that T cell-driven inflammation decreased the abundance of microbiome-encoded bile salt hydrolase (BSH) genes and reduced the levels of unconjugated and microbe-derived bile acids.
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Author Correction: Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy - Nature Medicine

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By Melody Smith, Jonas Schluter, Ying Taur, Jae Park, Tania Jain, Miguel-Angel Perales, Craig W. Freyer, Elise Chong, Michel Sadelain, Renier J Brentjens, Carl June, Jonathan Peled, Andrea Facciabene, Maria Lia Palomba, Aishat Olaide Afuye
| Nature Verified
Author notes These authors contributed equally: Anqi Dai, Andrea Facciabene, Guido Ghilardi, Marcel R. M. van den Brink, Marco Ruella. These authors jointly supervised this work: Andrea Facciabene, Marcel R. M. van den Brink, Marco Ruella. Authors and Affiliations Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA Melody Smith, Anqi Dai, John B. Slingerland, Pamela S.
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