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UBE2M as a bridge spanning neddylation and cell cycle regulation in colorectal adenocarcinoma - Experimental & Molecular Medicine
Abstract Protein neddylation is a post-translational modification process that modifies the functional state of proteins by conjugating NEDD8, a ubiquitin-like polypeptide, to the lysine residues of substrates. In various cancers, neddylation is upregulated and implicated in cancer progression via modulating cell cycle-related proteins. However, in colorectal cancer (CRC), the relationship between neddylation and the cell cycle remains incompletely understood.
Systematic Comparison of Anti‐Obesity Effects Among Three Characteristic Aroma‐Type Liubao Teas Based on Anti‐Inflammatory and Lipid‐Lowering Activities
1 Introduction Obesity is a multifactorial metabolic disorder marked by excessive fat accumulation and chronic inflammation. Chronic energy surplus causes adipose tissue dysfunction, leading to adipocyte hypertrophy and hyperplasia. These alterations promote comorbidities such as cardiovascular disease, nonalcoholic fatty liver disease (NAFLD), inflammatory bowel disease (IBD), cancers, and neuropsychological disorders (Hotamisligil 2006).
Visible‐Light‐Induced Synthesis of α‐Hydroxy Ketones From α‐Keto Acids Under Mild Conditions
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that supports the findings of this study are available in the Supporting Information of this article. Supporting Information Filename Description adsc70217-sup-0001-SuppData-S1.pdf2.1 MB Supplementary Material References 1For Selected Papers, See: , , and , Journal of Agricultural and Food Chemistry 69 (2021): 15314–15324. 2, , , et al., Energy & Environmental Science 17 (2024): 183–189.
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