Ying Wei
United States
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Repurposing the evolutionary fitness of marine bacteria for water-conserving conversion of lignin-derived carbon
Abstract Reverting waste carbon into chemicals and materials with minimal freshwater reliance is essential for a sustainable future. Here, we report the establishment of a blue biological scheme by repurposing the evolutionary fitness of the marine bacterium Roseovarius nubinhibens for efficient conversion of lignin-derived carbon into valuable chemicals with seawater as a water source. We create independency of the superior catalytic capacity of R.
Downregulation of alcohol dehydrogenase family proteins suggests disrupted retinol metabolism in neonatal respiratory distress syndrome: an umbilical cord blood proteomics study
Abstract Objective: Neonatal respiratory distress syndrome (NRDS) is a prevalent complication in preterm infants, characterized by severe pulmonary dysfunction and elevated mortality rates. To systematically profile the umbilical cord blood proteome in neonates with NRDS, aiming to identify and explore their potential pathological mechanisms.
Circular RNA MCM3 recruits USP49 to stabilize PTBP1 and promote cisplatin resistance in cervical squamous cell carcinoma
Abstract Circular RNA MCM3 is upregulated in platinum-resistant cervical squamous cell carcinoma (CSCC) and is associated with poor patient prognosis. However, its role in chemoresistance and the underlying mechanism remain undefined. Here, we demonstrate that circMCM3 drives cisplatin resistance both in vitro and in vivo by enhancing cell proliferation, inhibiting apoptosis and reducing DNA damage.
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