Ying-wu Lin
As seen in:
Color Research & Application,
Nature,
MDPI,
ACS Publications,
Royal Society of Chemistry
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Designing multifunctional peroxidases by modifying the heme distal site in myoglobin
Abstract Significant achievements have been made in the design of functional metalloenzymes. However, more convenient and versatile approaches are still needed to design multifunctional heme enzymes with broader substrate scope for potential applications such as bioremediation.
Structural insights into clonal restriction and diversity in T cell recognition of two immunodominant SARS-CoV-2 nucleocapsid epitopes - Nature Communications
Abstract T cells play a crucial role in clearing SARS-CoV-2 and in forming long-term memory responses to that coronavirus. The highly immunogenic nucleocapsid (N) protein of SARS-CoV-2 is much more conserved than the spike (S) protein across variants of concern, making it an attractive vaccine target for activating cytotoxic CD8+ T cells. Of particular interest are the immunodominant N epitopes LLL and SPR.
Total Synthesis of Brevitaxin
CCDC 2322418 and 2322420 contain the supplementary crystallographic data for this paper. These data can be obtained free of charge via www.ccdc.cam.ac.uk/data_request/cif, or by emailing data_request@ccdc.cam.ac.uk, or by contacting The Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, UK; fax: +44 1223 336033. Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions.
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