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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
An LRR-truncated NLR natural variant confers dual resistance to drought and blast in rice
Abstract Climate change threatens global food security by imposing concurrent abiotic and biotic stresses on major crops such as rice. Genetic resources conferring dual resistance to drought and blast disease are rare, limiting the development of climate-resilient crops. Here, using a genome-wide association study, we identify NLR8-Hap2, a natural allele of the rice resistance gene NLR8 that enhances resistance to drought and blast disease.
Diagnostic performance and antibiotic impact of droplet digital PCR in suspected sepsis: the PROGRESS trial
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Abstract Currently, tools to dynamically monitor pathogen load and guide antibiotic adjustment in suspected sepsis are limited. In this prospective, multicenter randomized trial (3:1, ddPCR vs standard care), 1,373 patients were followed for 90 days. The primary outcome was diagnostic efficacy; secondary outcomes included mortality and SOFA. ddPCR showed higher detection positivity (54.1% vs 21.6%, p < 2 × 10−16), faster turnaround, and sensitivity of 80.6%.
By Haocheng Zhang, Ke Xin Lin, Xinlei Xu, Qiaoyan Yue, Xiang Li, Xiaohua Chen, Lina Chen, Yan Huang, Ying Ye, Tingting Su, Jingye Pan, Weiqin Li, Shuang xiao, Xiaoxia Geng, Jingjing Zheng, Lijing Jiang, Jie Chen, Shengguo Zhang, Yadi Liu, Jun Yin, Aiming Zhou, Lu Ke, Qiuping Huang, Li Chen, Ting Feng, Ruilan Wang, Jingwen Ai, Wenhong Zhang, Hejuan Du
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Nature
Verified
Multicentre randomised controlled trial of a nurse-led family intervention on post-traumatic stress symptoms in families of children with cancer in China: protocol for the SCCIP-N trial
Neoplasms Psychosocial Intervention Randomized Controlled Trial Child This study is a prospective, parallel-group randomised controlled trial, which reduces selection bias and confounding. The intervention is based on a previously validated, culturally adapted programme specifically optimised for the Chinese demographic. The study incorporates self-reported and objective outcome measures to enhance the comprehensiveness of outcome assessment.
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