Yingbing Wang

OPPORTUNITY TO ELEVATE CARE IN AN ERA OF DISEASE-MODIFYING THERAPY The advent of Aβ-targeting therapies has created a need for more reliable imaging approaches that not only establish eligibility for treatment but also support monitoring of therapeutic response and long-term management. Visual reads have variability across raters (5%–15%), especially near the positivity threshold or in cases with atypical tracer distribution (e.g., focal uptake or technical artifacts).

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Editor’s summary The term “Long Covid” covers a diverse array of symptoms that an individual might experience weeks to years after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Many drivers of Long Covid have been proposed, with supporting data for each. Here, Peluso et al. provide compelling evidence for two potential contributors: persistent SARS-CoV-2 and aberrant T cell activation.