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Study on Performance of Integrated Thermal Management Strategy for Hybrid Electric Vehicles Under Low-Temperature Conditions
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Genetic identification of familial hypercholesterolemia within whole genome sequences in 6820 newborns
1 INTRODUCTION Familial hypercholesterolemia (FH) is a relatively common inherited disorder of lipid metabolism, characterized by elevated low-density lipoprotein cholesterol (LDL-C) levels and premature cardiovascular disease (CVD).1 LDLR, APOB and PCSK9 are members of the LDLR pathway, which is responsible for maintaining cholesterol levels of plasma and intracellular.
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