Yingdong Qu
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Full article: Research Progress on the Clinical Application of Remimazolam Outside the Operating Room: A Review of Pharmacological Characteristics, Clinical Effects, and Safety
Abstract Remimazolam is a novel ultra-short-acting benzodiazepine sedative, which has shown great promise in clinical scenarios such as outpatient surgeries, endoscopic examinations, intensive care units, and emergency departments due to its rapid onset, adjustable sedation level, and fast metabolic clearance. Currently, there is no consensus on the clinical application of remimazolam in non-operating room anesthesia.
Research Progress on the Clinical Application of Remimazolam Outside t
Back to Journals » Clinical Pharmacology: Advances and Applications » Volume 17 Authors Luo H, Zhou C , Qu Y, Kuang X Received 25 August 2025 Accepted for publication 4 December 2025 Published 18 December 2025 Volume 2025:17 Pages 329—337 DOI https://doi.org/10.2147/CPAA.S563154 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Arthur E.
The Effects of Different Administration Regimens of Berberine Hydrochloride on the Pharmacokinetics of Sirolimus in Rats
1 Introduction Sirolimus, also known as rapamycin, is a third-generation immunosuppressant with multiple effects such as antifungal, antitumor, and immunosuppressive. As a dual substrate of CYP3A4 and P-gp, sirolimus has shown wide application value in organ transplantation therapy [1, 2]. However, it is prone to complex interactions with multiple drugs [3]. Berberine hydrochloride (BBR) has an effect on CYP3A and P-gp [4, 5].
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