Yingge Cong

Abstract Cancer is a leading global cause of morbidity and mortality, with inter- and intra-tumor heterogeneity contributing to suboptimal therapeutic outcomes. While genomic profiling has advanced precision oncology, many tumors lack targetable mutations, underscoring the need for functional assays. Here, we present a drug sensitivity testing platform for patient-derived organoids (PDOs) based on active-matrix digital microfluidics (AM-DMF).

Abstract : Nowadays, bacterial infections are attracting great attention for the research and development of new antimicrobial agents. As one of the quinolones, ciprofloxacin (CI) has a broad-spectrum, strong antibacterial effect. However, the clinical use of ciprofloxacin is limited by drug resistance. Ciprofloxacin carbon dots (CCDs) with enhanced antibacterial activity and copper-doped ciprofloxacin carbon dots (Cu-CCDs) were synthesized by a simple hydrothermal method.

Research Article Dr. Yingge Cong, State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun, 130012 P. R. China CAS Key Laboratory of Bio Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, 215163 P. R. China These authors contributed equally to this work.