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Dual Aptamers-Based SETDB1 PROTACs as Effective Anti-Tumor Strategies for Breast Cancer (Adv. Sci. 18/2026)
Advanced Hub Main Navigation Menu Guo, Y., Lv, Y., Huang, S., Liu, C., Ouyang, Y., Lan, B. and Xuan, C. (2026), Dual Aptamers-Based SETDB1 PROTACs as Effective Anti-Tumor Strategies for Breast Cancer (Adv. Sci. 18/2026). Adv. Sci., 13: e74638. https://doi.org/10.1002/advs.74638 Scite metrics Explore this article's citation statements on scite.ai powered by Generating QR code Select Format Something went wrong while generating your QR code. Please try again in a moment.
Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer
1 Introduction Targeted protein degradation (TPD) technology has emerged as a powerful strategy for targeting traditionally “undruggable” proteins, significantly expanding the range of druggable targets. This innovative approach utilizes a recognition moiety that selectively binds to the target protein, facilitating its degradation through the protein hydrolysis pathway [1].
First-line treatment with gefitinib in combination with bevacizumab and chemotherapy in advanced non-squamous NSCLC with EGFR-mutation - BMC Cancer
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The study was conducted following the principles of the Helsinki Declaration, and written informed consent was obtained from all patients prior to enrollment.
By Lu Wang Verified, Weihong Zhang, Yuan Meng, Yang Wang, Meng Shen, Li Zhou Verified, Runmei Li, Yingge Lv, Shengguang Wang, Xiubao Ren, Liang Liu, Yanjuan Xiong
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BMC Cancer
Verified
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