Yingguo Li

Abstract Click to copy section linkSection link copied! Self-assembled cages have emerged as nanoscopic reactors that emulate enzymatic pockets, where confined cavities preorganize substrates, stabilize intermediates, and modulate transition states through supramolecular interactions. Here we harness this confined effect to address the long-standing challenge of enantioselective catalysis with nonprecious metals.

1 Introduction Hydrogen peroxide is a versatile and environmentally friendly oxidant with extensive applications in chemical synthesis,[1] medical sterilization[2] and energy conversion.[3] However, the industrial-scale production of H2O2 predominantly relies on the anthraquinone oxidation process, which suffers from several inherent drawbacks, including serious waste and high energy consumption.[4] Thus, the development of efficient, clean, and sustainable H2O2 production methods is crucial...