Yinghui Gao
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An orthogonal RNA aptamer for targeted RNA regulation in phase-separated subcellular compartments
Abstract Subcellular compartments organize RNAs into phase-separated condensates, significantly influencing RNA metabolism. However, the study of how specific RNAs regulate interacting factors and their phenotypic outcomes is hindered by the lack of advanced imaging and regulation tools. To address this, we developed an orthogonal RNA aptamer system, Clivia-HT, which integrates a fluorescent imager with a ribonuclease-targeting chimera (RIBOTAC) degrader.
Effect Heterogeneity of CPAP on MACE by Nocturnal Hypoxia Burden in Older Adults OSAS: A Propensity Score Matching Study
Back to Journals » Clinical Interventions in Aging » Volume 21 Authors Zhao L , Wang T, Gao Y, Ding Y, Zhang Y, Rui D, Zhao Z , Xue X, Zhao X, Liu L, Zeng Y Received 17 February 2026 Accepted for publication 4 June 2026 Published 30 June 2026 Volume 2026:21 603046 DOI https://doi.org/10.2147/CIA.S603046 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Maddalena Illario Libo Zhao Tianyi Wang Yinghui Gao Yaodong Ding...
Effect of obstructive sleep apnoea syndrome combined with renal insufficiency on all-cause mortality in elderly patients in China: a prospective cohort study
STRENGTHS AND LIMITATIONS OF THIS STUDY This was a prospective cohort study of the risk of all-cause death in patients with obstructive sleep apnoea syndrome combined with renal insufficiency. This was a large multicentre prospective cohort study. We calculated glomerular filtration rate (GFR) based on cystatin C (Cys-C) to determine kidney function, which may be skewed.
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