Yinghui Wang

The influence of hydrogen bond on the reaction of guanine and hydroxyl radical: DFT calculation in C(H+)GC motif A comprehensive theoretical investigation was performed to illuminate the influence of hydrogen bond (H-bond) on the obscure reaction of hydroxyl radical (HO•) and guanine (G) by selecting the building block of parallel triplex DNA, C(H+)GC, as the model. By mapping the energy profiles for both addition and hydrogen abstraction reaction, the favorable pathway is predicted.

Ultrasensitive fluorescence immunoassay of pepsinogen I based on enzyme-triggered decomposition of AuNCs/MnO2 Gastric cancer is a prevalent malignant tumor of the gastrointestinal tract accompanied by a high mortality rate; therefore, early gastric cancer screening is critical for improving patient survival.

Theoretical insight into the reaction mechanism of hydroxyl radical and guanine in G-quadruplex DNA Abstract A DFT investigation was performed to illuminate the obscure mechanism of hydroxyl radical (OH•) and guanine in G-quadruplex by mapping the energy profiles for both addition and hydrogen abstraction reaction.