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Yinging Xia

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Prenatal exposure to hypertensive disorders and adolescent brain white matter development

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By Vida Rebello, Hedyeh Ahmadi, Andrew O Odegaard, Veronica Vieira, Marybel Gonzalez, Eric C. Kan, Bernadette Boden-Albala, Kristina A Uban, Yinging Xia, Nicole M. Talge
| Nature Verified
Abstract Hypertensive disorders of pregnancy (HDP) are associated with altered in utero neurodevelopment, yet long-term impact on adolescent white matter architecture remains unclear, particularly by HDP subtype and sex. While preeclampsia/eclampsia (P/E) is clinically more severe, pregnancy-related hypertension (PR-HTN) may involve longer in-utero exposure to hemodynamic stress. This study examined how distinct HDP exposures influence longitudinal white matter measures in adolescents.
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