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Yingjia Pan on Muck Rack

Yingjia Pan

As seen in: Nature
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Programmable enhancement of endogenous mRNA translation through CRISPR-guided epitranscriptomic regulation

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By Yaxian Cheng, Guanglin Zhu, Xinzhi Zhou, Yiran Liu, Xiaomeng Guo, Dongfang Li, Cui Hua Liu, Xiaoxiang Hu, Guoqing Shao, Zhimin Gu, Lubin Liu, Wen Jiang, Guo Li, Yingjia Pan, Guoya Liao
| Nature Verified
Dear Editor, Gene expression is regulated at multiple levels, including transcription, RNA processing, and translation1. Conventional gene-editing technologies such as CRISPR-Cas92 and DNA base editors3 induce permanent genomic alterations through unpredictable DNA repair pathways. Cas13-based systems and derived RNA editors4 can alter transcript abundance and introduce off-target RNA effects.
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