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FGFR1 copy number gain is independently associated with shorter progression-free survival in advanced lung squamous cell carcinoma treated with first-line immune checkpoint inhibitor-based therapy
Abstract Background: Lung squamous cell carcinoma (LUSC) represents a predominant subtype of non-small cell lung cancer (NSCLC) with scarce effective targeted therapeutic options, rendering immune checkpoint inhibitor (ICI)-based regimens the standard first-line treatment for advanced-stage disease.
Overcoming biological inertness: multifaceted strategies to optimize PEEK bioactivity for interdisciplinary clinical applications
Overcoming biological inertness: multifaceted strategies to optimize PEEK bioactivity for interdisciplinary clinical applications Polyether ether ketone (PEEK), characterized by a comparable elastic modulus to human bone with high wear resistance, radiolucency, and biocompatibility, demonstrates considerable promise for clinical applications.
Desert Beetle Inspired Heterogeneous Electrode for Large Current Density Hydrogen Evolution Reaction
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202425150-sup-0001-SuppMat.pdf1.6 MB Supporting Information adfm202425150-sup-0002-MovieS1.mp413.4 MB Supplemental Movie 1 adfm202425150-sup-0003-MovieS2.mp46.5 MB Supplemental Movie 2 adfm202425150-sup-0004-MovieS3.mp48.6 MB Supplemental Movie 3 References 1a) , Science 2004, 305, 972; b) , , Science 2022, 376, 348. 2a) , , , , , , , , Nat. Mater.
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